Parcours Biologie cellulaire et développement

The recent advances in cell and developmental biology (including imaging, stem cell biology and systems biology) integrate biological mechanisms at multiple scales, from the level of molecular complexes to the whole organism. These fundamental discoveries will have significant therapeutic benefits, notably in cancer biology and regenerative medicine. The “Gene, Cell, and Development” (GCD) Master course explores molecular, genetic and epigenetic mechanisms from cell to organism. This training provides the concepts and methods to understand the variety of processes controlling cell biology during development, differentiation, and disease.

Pré-requis

Access to GCD Course implies mastering the theoretical and methodological knowledge of the first year of masters in the following subjects: cell biology,  developmental biology, and genetics. This knowledge may have been acquired by various combinations of the courses (called Teaching Units, or UE) proposed in the teaching Platforms called ‘major’ during first year of Master. The Majors “Platforms” recommended are “Molecular and Cell Biology” or “Physiology and  Physiopathology”. We also strongly recommend that candidates follow the internship Teaching Unit.

Objectifs

The “Gene, Cell, and Development” Master course is an advanced course on cell biology during development, diff erentiation, and disease. A series of lectures, practical courses and personal research will enable the students to understand the recent developments and the current challenges of research around those  themes. Science and medical students will thus acquire theoretical knowledge and practical skills essential for them to understand the research topics of their  future host laboratories, wherever they will pursue academic, applied or clinical research.

Débouchés

The main job prospects after this second year of masters will be in fundamental and applied research in France or abroad. This can be achieved mostly by  pursuing a Ph.D. thesis, but a few engineer level positions are open after a master thesis. Positions will be found in major academic research institutes, affiliated to University, CNRS, INSERM, INRA, or CEA. The Ph.D. thesis will open the path to an academic research career. Aside academia, other job  openings will be found in private companies, as this master degree provides background to become project manager in research and development, clinical research investigator or
research engineer. This training is also recommended for clinicians and medical students willing to acquire a fundamental knowledge in cell and developmental biology and pursue clinical research.

Recherche

The students following the GCD master will work for six months in a host research laboratory, to develop a personal research project, under the close  supervision of a mentor. This project will be prepared beforehand, during a specifi c Teaching Unit, to explore the litterature of the proposed subject and to  prepare the outline of the final scientific report. At the end of the research, a written manuscript and and oral presentation (in French or English) will be  evaluated by the master committee. In addition to being an immersion into laboratory research, this training potentially sets the basis for a longer Ph.D. project.

Lieux d'enseignements

Institut Curie, Orsay Campus. Université Paris-Sud

Contacts

• Anne-Hélène MONSORO-BURQ, anne.monsoro-burq @ u-psud.fr
• Isabelle GUENAL, isabelle.guenal @ uvsq.fr